CentroidAlign -- RNA alignment tool
What you can do:
Perform multiple sequence alignment of structured RNA.
Highlights:
- CentroidAlign is a novel estimator for multiple alignments of structured RNAs, based on maximizing the expected accuracy of predictions.
- The maximum expected accuracy (MEA) estimator for pairwise alignment of RNA sequences maximizes the expected sum-of-pairs score (SPS) of a predicted alignment under a probability distribution of alignments given by marginalizing the Sankoff model.
- It can handle uncertainty of secondary structures and alignments because it considers all the secondary structures and all the pairwise alignments as input sequences.
Keywords:
- RNA
- structured RNA
- RNA sequence alignment
- multiple RNA sequence alignment
- multiple sequence alignment
- structured RNA alignment
Literature & Tutorials:
This record last updated: 11-05-2009