FRODOCK -- Fast Rotational DOCKing tool
What you can do:
Find information about how proteins dock with each other.
Highlights:
- FRODOCK performs an exhaustive 6D docking between two protein structures.
- This approximation is able to generate very efficiently many potential predictions of how these two proteins could interact.
- Since this is an initial stage exhaustive docking, a second refinement or scoring stages is expected, but the excellent accuracy results obtained with standard benchmarks permit its usage directly as a first protein-protein docking approach.
- Since it is a rigid-body approximation, this is valid only when reduced conformational changes upon binding are expected.
Keywords:
- protein-protein interaction
- protein-protein docking
Literature & Tutorials:
This record last updated: 11-12-2009