HRTBLDb -- Hormone Receptor Target Binding Loci Database

URL:
http://motif.bmi.ohio-state.edu/hrtbldb/
What you can do:
Find information about hormone protein interactions.
Highlights:
  • The Hormone Receptor Target Binding Loci is a data management system organize data about the estrogen receptor (ER), the androgen receptor (AR) and glucocorticoid receptor (GR).
  • This database contains hormone receptor binding regions (binding loci) from in vivo ChIP-based high-throughput experiments as well as in silico, computationally predicted, binding motifs and cis-regulatory modules for the co-occurring transcription factor binding motifs, which are within a binding locus.
  • It also contains individual binding sites whose regulatory action has been verified by in vitro experiments.
  • The current version contains 44 673 binding elements with 114 hormone response elements which are verified by in vitro experiments; 75 binding motifs which occur with a hormone response element and whose co-regulatory action is verified by in vitro experiments; 18 472 binding loci from in vivo experiments; and 26 012 computationally predicted binding motifs.
Keywords:
  • hormone
  • hormone receptor
  • estrogen receptor
  • androgen receptor
  • glucocorticoid receptor
  • ChIP
  • chromatin immunoprecipitate
  • hormone receptor transcriptional regulation
Literature & Tutorials:
PubMed Link: HRTBLDb: an informative data resource for hormone receptors target binding loci
This record last updated: 12-1-09
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