Dynamic Proteomics -- Protein Localization Database

URL:

http://www.weizmann.ac.il/mcb/UriAlon/DynamProt/index.html

What you can do:

Tracking the levels and locations of a human proteins in cells over time using a library of annotated reporter cell clones.

Highlights:

Dynamic Proteomics is a database for the proteins studied by Cohen et al.
Each cell-line clone in the library of annotated reporter cell clones (LARC) has a protein tagged with yellow fluorescent protein, expressed from its endogenous chromosomal location, under its natural regulation.
The Dynamic Proteomics interface facilitates searches for genes of interest, downloads of protein fluorescent movies and alignments of dynamics following drug addition.
Each protein in the database is displayed with its annotation, cDNA sequence, fluorescent images and movies obtained by the time-lapse microscopy.
The protein dynamics in the database represents a quantitative trace of the protein fluorescence levels in nucleus and cytoplasm produced by image analysis of movies over time.
Furthermore, a sequence analysis provides a search and comparison of up to 50 input DNA sequences with all cDNAs in the library.
The raw movies may be useful as a benchmark for developing image analysis tools for individual-cell dynamic-proteomics.

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Literature & Tutorials:

This record last updated: 03-01-2010