SelTarbase -- Selective Targets Database

URL:
http://motif.bmi.ohio-state.edu/hrtbldb/
What you can do:
Find information about mononucleotide repeat tracts and microsatellite instability in tumors.
Highlights:
  • The Selective Targets database is a curated database of a growing number of public MNR mutation data in microsatellite unstable human tumors.
  • Regression calculations for various MSI-H tumor entities indicating statistically deviant mutation frequencies predict TGFBR2, BAX, ACVR2A and others that are shown or highly suspected to be involved in MSI tumorigenesis.
  • Many useful tools for further analyzing genomic DNA, derived wild-type and mutated cDNAs and peptides are integrated.
  • A comprehensive database of all human coding, untranslated, non-coding RNA- and intronic MNRs (MNR_ensembl) is also included.
Keywords:
  • MMR deficiency
  • Deficient DNA mismatch repair
  • hereditary non-polyposis colorectal cancer
  • HNPCC/ Lynch syndrome
  • Microsatellite instability
  • coding mononucleotide repeat tract
Literature & Tutorials:
PubMed Link: SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology
This record last updated: 03-16-2010
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