RegPrecise -- Regulon Prediction Database

What you can do:
Find information about predicted regulons in prokaryotic transcription regulation.
Highlights:
  • The RegPrecise database was developed for capturing, visualization and analysis of predicted transcription factor regulons in prokaryotes that were reconstructed and manually curated by utilizing the comparative genomic approach.
  • The reconstructed regulons include transcription factors, their cognate DNA motifs and regulated genes/operons linked to the candidate transcription factor binding sites.
  • It allows for browsing the regulon collections for: (i) conservation of DNA binding sites and regulated genes for a particular regulon across diverse taxonomic lineages; (ii) sets of regulons for a family of transcription factors; (iii) repertoire of regulons in a particular taxonomic group of species; (iv) regulons associated with a metabolic pathway or a biological process in various genomes.
  • The initial release of the database includes approximately 11,500 candidate binding sites for approximately 400 orthologous groups of transcription factors from over 350 prokaryotic genomes.
  • Majority of these data are represented by genome-wide regulon reconstructions in Shewanella and Streptococcus genera and a large-scale prediction of regulons for the LacI family of transcription factors.
  • Another section in the database represents the results of accurate regulon propagation to the closely related genomes.
Keywords:
  • regulon
  • prokaryotic regulon
  • transcription factor regulon
  • prokaryote transcription
  • prokaryote gene expression
  • gene expression regulation
This record last updated: 04-29-2010
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