RegPrecise -- Regulon Prediction Database
What you can do:
Find information about predicted regulons in prokaryotic transcription regulation.
Highlights:
- The RegPrecise database was developed for capturing, visualization and analysis of predicted transcription factor regulons in prokaryotes that were reconstructed and manually curated by utilizing the comparative genomic approach.
- The reconstructed regulons include transcription factors, their cognate DNA motifs and regulated genes/operons linked to the candidate transcription factor binding sites.
- It allows for browsing the regulon collections for: (i) conservation of DNA binding sites and regulated genes for a particular regulon across diverse taxonomic lineages; (ii) sets of regulons for a family of transcription factors; (iii) repertoire of regulons in a particular taxonomic group of species; (iv) regulons associated with a metabolic pathway or a biological process in various genomes.
- The initial release of the database includes approximately 11,500 candidate binding sites for approximately 400 orthologous groups of transcription factors from over 350 prokaryotic genomes.
- Majority of these data are represented by genome-wide regulon reconstructions in Shewanella and Streptococcus genera and a large-scale prediction of regulons for the LacI family of transcription factors.
- Another section in the database represents the results of accurate regulon propagation to the closely related genomes.
Keywords:
- regulon
- prokaryotic regulon
- transcription factor regulon
- prokaryote transcription
- prokaryote gene expression
- gene expression regulation
Literature & Tutorials:
This record last updated: 04-29-2010