PANDORA -- Protein ANnotation Diagram ORiented Analysis
What you can do:
Find information about protein sequence annotations.
Highlights:
- PANDORA is a web server which functions as a platform for the advanced biological analysis of sets of genes, proteins, or proteolytic peptides.
- The input set is mapped to a set of corresponding proteins.
- Then, an analysis of the protein set produces a graph-based hierarchy which highlights intrinsic relations amongst biological subsets, in light of their different annotations from multiple annotation resources.
- PANDORA integrates a large collection of annotation sources (GO, UniProt Keywords, InterPro, Enzyme, SCOP, CATH, Gene-3D, NCBI taxonomy and more) that comprise approximately 200 000 different annotation terms associated with approximately 3.2 million sequences from UniProtKB.
- Statistical enrichment based on a binomial approximation of the hypergeometric distribution and corrected for multiple hypothesis tests is calculated using several background sets, including major gene-expression DNA-chip platforms.
- Users can also visualize either standard or user-defined binary and quantitative properties alongside the proteins.
Keywords:
- protein sequence annotation
- protein functional annotation
- gene expression
- mass spectrometry proteomics
- MS proteomics
Literature & Tutorials:
This record last updated: 06-21-2010