MatrixDB -- extracellular matrix interaction database

What you can do:
Find information about the interactions of extracellular proteins and polysaccharides.
Highlights:
  • MatrixDB is a freely available database focused on interactions established by extracellular proteins and polysaccharides.
  • It takes into account the multimeric nature of several extracellular protein families for the curation of interactions, and reports interactions with individual polypeptide chains or with multimers, considered as permanent complexes, when appropriate.
  • MatrixDB is a member of the International Molecular Exchange consortium (IMEx) and has adopted the PSI-MI standards for the curation and the exchange of interaction data.
  • It stores experimental data from our laboratory, data from literature curation, data imported from IMEx databases, and data from the Human Protein Reference Database.
  • It is focused on mammalian interactions, but aims to integrate interaction datasets of model organisms when available.
  • It provides direct links to databases recapitulating mutations in genes encoding extracellular proteins, to UniGene and to the Human Protein Atlas that shows expression and localization of proteins in a large variety of normal human tissues and cells.
  • MatrixDB allows researchers to perform customized queries and to build tissue- and disease-specific interaction networks that can be visualized and analyzed with Cytoscape or Medusa.
Keywords:
  • extracellular protein
  • extracellular polysaccharides
  • protein-polysaccharide interaction
  • polysaccharide-protein interaction
Literature & Tutorials:
This record last updated: 06-14-2011
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