ThYme -- Thioester-active enzYme database
What you can do:
Find sequence and structure information about thioester-active enzymes.
Highlights:
- The ThYme database has been constructed to bring together amino acid sequences and 3D (tertiary) structures of all the enzymes constituting the fatty acid synthesis and polyketide synthesis cycles.
- These enzymes are active on thioester-containing substrates, specifically those that are parts of the acyl-CoA synthase, acyl-CoA carboxylase, acyl transferase, ketoacyl synthase, ketoacyl reductase, hydroxyacyl dehydratase, enoyl reductase and thioesterase enzyme groups.
- These groups have been classified into families, members of which are similar in sequences, tertiary structures and catalytic mechanisms, implying common protein ancestry.
- ThYme is continually updated as sequences and tertiary structures become available.
Keywords:
- thioester-active enzyme
- fatty acid synthesis
- polyketide synthesis
- thioester-active enzyme structure
- thioester-active enzyme sequence
Literature & Tutorials:
PubMed Link: ThYme: a database for thioester-active enzymes.
This record last updated: 06-14-2011