PCDB -- Protein Conformational diversity DataBase
What you can do:
Find information about all the structures a given protein can take.
Highlights:
- PCDB is a database of protein conformational diversity.
- For each protein, the database contains the redundant compilation of all the corresponding crystallographic structures obtained under different conditions.
- These structures could be considered as different instances of protein dynamism.
- As a measure of the conformational diversity we use the maximum RMSD obtained comparing the structures deposited for each domain.
- The redundant structures were extracted following CATH structural classification and cross linked with additional information.
- In this way it is possible to relate a given amount of conformational diversity with different levels of information, such as protein function, presence of ligands and mutations, structural classification, active site information and organism taxonomy among others.
- Currently the database contains 7989 domains with a total of 36581 structures from 4171 different proteins. The maximum RMSD registered is 26.7 Å and the average of different structures per domain is 4.5.
Keywords:
- protein conformational diversity
- protein conformations
- protein crystallographic structure
Literature & Tutorials:
This record last updated: 06-14-2011