General protein sequence databases, sequence similarity search and alignment tools
Detect sub-family specific residues in alignments.
Compare protein sequences by their dynamics.
Switch your sequence between multiple sequence alignment formats.
Determine protein function for a DNA sequence or find genomic sequence corresponding to a gene.
Compare two nucleotide or protein sequences using a local alignment algorithm.
Retrieve user-defined subsets of homologous protein sequences.
Search for orthologous groups
Quickly find sequences of 95% and greater similarity of length 40 bases or more for DNA or 80% and greater similarity of length 20 amino acids or more for protein in a genome.
A tool to graphically study local amino acid composition in protein sequences of a multiple sequence alignment.
Produce functional annotations of new bacterial and archaeal genomes.
Construct local alignments and detect homology based on the comparison of multiple sequence alignments
Detect and analyze coordinated substitutions in multiple alignments of protein sequences.
Identify distant homologous protein sequences.
Find information about toxin-like protein sequences.
Perform multiple DNA or protein sequences alignments.
Automatically calculate evolutionary conservation scores of key amino acid residues and map them on protein structures.
Align multiple DNA or protein sequences.
Conduct a variety of analysis of DNA and protein sequences.
Use this blast tool to blast query sequence against your own collection of sequences.
Compare two sequences with either local or global alignment algorithms.
Perform high-quality multiple protein sequence alignments.
Conduct protein alignment analysis, multiple sequence alignment, and comparative modeling.
Conduct multiple alignments and subsequent quality evaluation.
Compare two protein or DNA sequences for local similarity and show the local sequence alignments.
Web server that computes multiple sequence alignments (MSAs) by running several MSA methods and combining their output into one single model.
Predict features in biological sequences.

Visualize and survey the model-training sequences to discover and characterize possible dependencies among protein sequences.
Generate allelic profiles to characterize strains of Neisseria meningitidis.
Search for protein sequence-related information based on whole-genome analysis.
Find similar sequences to a query protein sequence from SWISS-PROT using an exhaustive true Smith and Waterman algorithm.
Perform multiple sequence alignment with hierarchical clustering.
Find similar sequences to a query sequence from various sequence databases.
Search for comprehensive information on protein.
Find information about potential functions of proteins.
Search for sequences, predicted GO molecular functions and predicted subcellular localizations of more than 107,000 proteins from 10 model organisms.
Convert a multiple sequence alignment of proteins and the corresponding DNA (or mRNA) sequences into a codon alignment.
Identify distantly related sequences in both nucleotide and amino acid sequence databases.
Produce lists of sequences from the Protein Data Bank (PDB) using a number of entry- and chain-specific criteria and mutual sequence identity.
Perform multiple protein sequence alignment and integrate information from database homology searches to generate a homology-extended multiple alignment.
Construct multiple protein sequence alignment
Construct alignments for multiple protein sequences and/or structures using information from sequence database searches, secondary structure prediction, available homologs with 3D structures and user-defined constraints.
A web server for protein sequence variability analysis tuned to facilitate conserved epitope discovery.
A searchable archive for peptide sequences and associated biological data.
Predict signal peptide sequences and their cleavage positions in bacterial and eukaryotic amino acid sequences.
A web-server that searches a protein sequence for CBS composed of user-specified amino acid types.
Search for evolutionarily conserved motif-like patterns in protein sequences.
A web server for protein remote homology detection.
Detect and analyze regions with short gapless repeats in protein sequences or alignments.
Find sequence repeats in a protein sequence.
Generate a random protein sequence.
Find sequences representing genomes, transcripts, and proteins.
Retrieve curated, non-redundant reference mRNA sequences from NCBI.
Translate a protein (amino acid) sequence to its corresponding nucleotide sequence.
Perform protein sequence alignment and phylogenetic tree building.
Search for similarities between proteins by simultaneous matching of multiple motifs.
Protein sequence database searching.
Visualize all "missing" protein regions in PDB.
Search protein/nucleotide databases with keywords and a sequence motif.
Find similar sequences to a query sequence from protein databases
Use a collection of bioinformatics tools at this portal site.
Retrieve comprehensive protein information
Search for comprehensive information on documented and predicted membrane transport protein.
Conduct and evaluate multiple sequence alignments for protein, DNA and RNA.
Conduct various analysis to protein sequences use a suite of software tools.
Conduct protein sequence and structure analysis using a suite of software tools.
Predict protein structure and function based on protein sequence.
Perform protein nucleotide sequence alignment.
Search a comprehensive repository of all protein sequences.
A central resource on protein sequences and functional annotation.
Search or download the Clustered sets of related sequences from UniProt.
Create representative, unbiased data sets of protein sequences.
Query multiple databases and user's datasets.
Prepare publication-quality pictures of DNA or protein multiple sequence alignments.
Retrieve protein orthologs and associated Gene Ontology terms from nine eukaryotic model organisms.
Compute multiple sequence alignments from partition function posterior probabilities.
Generate sequence logos from DNA and protein sequences.
Search and analyze hypothetical protein sequences.