KEGG -- resource for deciphering the genome
What you can do:
Search a database of biological systems that integrates genomic, chemical and systemic functional information.
Highlights:
- KEGG provides a reference knowledge base for linking genomes to life through the process of PATHWAY mapping, which is to map, for example, a genomic or transcriptomic content of genes to KEGG reference pathways to infer systemic behaviors of the cell or the organism.
- In addition, KEGG provides a reference knowledge base for linking genomes to the environment, such as for the analysis of drug-target relationships, through the process of BRITE mapping.
- KEGG BRITE is an ontology database representing functional hierarchies of various biological objects, including molecules, cells, organisms, diseases and drugs, as well as relationships among them.
- KEGG PATHWAY is now supplemented with a new global map of metabolic pathways, which is essentially a combined map of about 120 existing pathway maps.
- In addition, smaller pathway modules are defined and stored in KEGG MODULE that also contains other functional units and complexes.
- The KEGG resource is being expanded to suit the needs for practical applications.
- KEGG DRUG contains all approved drugs in the US and Japan, and KEGG DISEASE is a new database linking disease genes, pathways, drugs and diagnostic markers.
Keywords:
- biological pathways prediction
- metabolic pathway prediction
- signal transduction pathway prediction
- computer simulation of life
- computer modeling of cellular processes
- chemical genomics
- ligands
Literature & Tutorials:
PubMed Link: The KEGG resource for deciphering the genome
2006 Update: From genomics to chemical genomics: new developments in KEGG
2008 Update: KEGG for linking genomes to life and the environment
2006 Update: From genomics to chemical genomics: new developments in KEGG
2008 Update: KEGG for linking genomes to life and the environment
This record last updated: 04-08-2008