RegulonDB (v6.0) -- gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation
What you can do:
Search for information on the transcriptional regulatory network of Escherichia coli K12.
Highlights:
- All the objects are supported by their corresponding evidences, now classified as strong or weak.
- Transcription factors are classified by origin of their effectors and by gene ontology class.
- Includes computational predictions for sigma(54) and five different promoter types of the sigma(70) family, as well as their corresponding -10 and -35 boxes.
- Includes 300 experimentally mapped promoters coming from our own high-throughput mapping efforts.
- RegulonDB v.6.0 now expands beyond transcription initiation, including RNA regulatory elements, specifically riboswitches, attenuators and small RNAs, with their known associated targets.
- The data can be accessed through overviews of correlations about gene regulation.
- RegulonDB associated original literature, together with more than 4000 curation notes, can now be searched with the Textpresso text mining engine.
Keywords:
- E. coli transcription regulation
- E. coli transcription factors
- TFs
- E. coli promoters
- E. coli operons
- E. coli regulons
- E. coli gene regulation
- E. coli transcriptional regulation
- E. coli growth conditions
- promoter analysis
- DNA-binding sites
- ribosome binding sites
- regulatory networks
- regulatory pathways
Literature & Tutorials:
PubMed Link: RegulonDB (v 4.0) -- Transcriptional Regulation, Operon Organization and Growth Conditions in Escherichia coli K-12
PubMed Link of the article on Version 5: RegulonDB (version 5.0): Escherichia coli K-12 transcriptional regulatory network, operon organization, and growth conditions
2008 Update: RegulonDB (v6.0) -- gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation
2011 Update: RegulonDB version 7.0: transcriptional regulation of Escherichia coli K-12 integrated within genetic sensory response units (Gensor Units).
PubMed Link of the article on Version 5: RegulonDB (version 5.0): Escherichia coli K-12 transcriptional regulatory network, operon organization, and growth conditions
2008 Update: RegulonDB (v6.0) -- gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation
2011 Update: RegulonDB version 7.0: transcriptional regulation of Escherichia coli K-12 integrated within genetic sensory response units (Gensor Units).
This record last updated: 03-03-2008