IsoFinder -- Computational Prediction of Isochores in Genome Sequences
What you can do:
Predict isochores at the genomic sequence level.
Highlights:
- Using recursive algorithm, the program leads to the decomposition of a chromosome sequence into long homogeneous genome regions (LHGRs) with well-defined mean G+C contents, each significantly different from the G+C contents of the adjacent LHGRs.
- Most LHGRs can be identified with Bernardi's isochores, given their correlation with biological features such as gene density, SINE and LINE (short, long interspersed repetitive elements) densities, recombination rate or single nucleotide polymorphism variability.
Keywords:
- isochores
- isochore prediction
- isochore maps
- G+C contents
- GC content
- DNA sequence analysis
Literature & Tutorials:
PubMed Link: IsoFinder
This record last updated: 05-03-2005