OligoDesign -- optimal design of LNA (locked nucleic acid) oligonucleotide capture probes for gene expression profiling

URL:
http://lnatools.com/
What you can do:
Design optimal LNA (locked nucleic acid) substituted oligonucleotides for functional genomics applications.
Highlights:
  • The OligoDesign software features recognition and filtering of the target sequence by genome-wide BLAST analysis in order to minimize cross-hybridization with non-target sequences.
  • Furthermore it includes routines for prediction of melting temperature, self-annealing and secondary structure for LNA substituted oligonucleotides, as well as secondary structure prediction of the target nucleotide sequence.
  • Individual scores for all these properties are calculated for each possible LNA oligonucleotide in the query gene and the
  • OligoDesign program ranks the LNA capture probes according to a combined fuzzy logic score and finally returns the top scoring probes to the user in the output.
Keywords:
  • Oligonucleotide Probes
  • DNA Probes
  • Gene Expression Profiling probes
  • microarray probes
  • Oligonucleotide Probe design tool
  • DNA Probe design tool
  • Gene Expression Profiling probe design tool
  • microarray probe design tool
  • locked nucleic acid oligonucleotide
Literature & Tutorials:
PubMed Link: OligoDesign -- optimal design of LNA (locked nucleic acid) oligonucleotide capture probes for gene expression profiling
This record last updated: 06-16-2005
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