CAMPO, SCR_FIND and CHC_FIND -- a suite of web tools for computational structural biology
What you can do:
Identify evolutionarily conserved features of protein structures using three software tools.
Highlights:
- Three methods have been developed and implemented as WWW tools, CAMPO, SCR_FIND and CHC_FIND, to analyze evolutionarily conserved residues (ECRs), structurally conserved regions (SCRs) and conserved hydrophobic contacts (CHCs) in protein families and superfamilies, on the basis of their 3D structures and the homologous sequences available.
- The programs identify protein segments that conserve a similar main-chain conformation, compute residue-to-residue hydrophobic contacts involving only apolar atoms common to all the 3D structures analyzed and allow the identification of conserved amino-acid sites among protein structures and their homologous sequences.
- The programs also allow the visualization of SCRs, CHCs and ECRs directly on the superposed structures and their multiple structural and sequence alignments.
Keywords:
- protein structure analysis tool
- protein structure alignment
- conserved structures
- conserved sequences
- conserved amino acid sites prediction tool
- protein Hydrophobicity
- protein structure comparison tool
- protein conformation analysis tool
- protein evolution
Literature & Tutorials:
This record last updated: 08-25-2005