SRide -- a server for identifying stabilizing residues in proteins
What you can do:
Identify stabilizing residues in protein structures.
Highlights:
- Residues expected to play key roles in the stabilization of proteins [stabilizing residues (SRs)] are selected by combining several methods based mainly on the interactions of a given residue with its spatial, rather than its sequential neighborhood and by considering the evolutionary conservation of the residues.
- A residue is selected as a stabilizing residue if it has high surrounding hydrophobicity, high long-range order, high conservation score and if it belongs to a stabilization center.
- SRs could be applied in protein engineering and homology modeling and could also help to explain certain folds with significant stability.
Keywords:
- stabilizing residues
- stabilizing residue prediction tool
- protein stability
- protein engineering tool
- protein homology modeling tool
- protein folds
Literature & Tutorials:
This record last updated: 11-14-2005