POCO -- discovery of regulatory patterns from promoters of oppositely expressed gene sets
What you can do:
Detect transcription factor binding sites in promoters of co-regulated genes.
Highlights:
- POCO discovers the over-represented patterns from either one or two promoter sets.
- pattern discovery is based on explicit enumeration of all possible patterns on the alphabet (A, C, G, T and N). The mean occurrences and SDs of the patterns are estimated using bootstrapping and their significance is assessed using ANOVA F-statistics, Tukey's honestly significantly difference test and P-values.
Keywords:
- transcription factor binding sites transcription factor binding site analysis tool
- DNA-binding sites
- cis-elements
- cis-regulatory elements
- promoter elements
- transcription factors
- cis-elements
- cis-regulatory modules analysis tool
- co-regulated genes
Literature & Tutorials:
This record last updated: 11-21-2005