iMOT -- An interactive package for the selection of spatially interacting motifs
What you can do:
Automatically identify spatially interacting motifs among distantly related proteins sharing similar folds and possessing common ancestral lineage.
Highlights:
- iMOT is an automated method for identifying conserved spatially interacting regions across proteins.
- Signatures of proteins are derived based on spatial interactions among sequentially conserved regions.
- Spatial interactions between conserved stretches of a protein are evaluated by calculations of pseudo-potentials that describe the strength of interactions.
- Such an evaluation permits the automatic identification of highly interacting conserved regions of a protein. Interacting motifs have been shown to be useful in searching for distant homologues and establishing remote homologies among the largely unassigned sequences in genome databases.
- Information on such motifs should also be of value in protein folding, modeling and engineering experiments.
Keywords:
- protein structures
- protein structure modeling
- protein folds
- protein motifs
- conserved protein motifs
- protein homology analysis
Literature & Tutorials:
This record last updated: 10-25-2006