YEASTRACT-DISCOVERER -- new tools to improve the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae
What you can do:
Find regulatory associations between transcription factors (TF) and target genes and identify complex motifs found to be over-represented in the promoter regions of co-regulated genes in yeast.
Highlights:
- This database contains over 30,990 regulatory associations between Transcription Factors (TFs) and target genes and includes 284 specific DNA binding sites for 108 characterized TFs.
- Computational tools are also provided to facilitate the exploitation of the gathered data when solving a number of biological questions, in particular the ones that involve the analysis of global gene expression results.
- In this new release, YEASTRACT includes DISCOVERER, a set of computational tools that can be used to identify complex motifs over-represented in the promoter regions of co-regulated genes.
- The motifs identified are then clustered in families, represented by a position weight matrix and are automatically compared with the known transcription factor binding sites described in YEASTRACT.
- Additionally, in this new release, it is possible to generate graphic depictions of transcriptional regulatory networks for documented or potential regulatory associations between TFs and target genes.
- The visual display of these networks of interactions is instrumental in functional studies.
- Tutorials are available on the system to exemplify the use of all the available tools.
Keywords:
- yeast transcription regulation
- Saccharomyces cerevisiae transcription regulation
- yeast regulatory motifs
- yeast regulator elements
- yeast DNA-binding sites
- yeast transcription factors
- yeast promoter elements
- yeast cis-regulatory elements
- yeast promoters
- yeast regulatory networks
- yeast regulatory sequences
- yeast regulons
Literature & Tutorials:
PubMed Link: The YEASTRACT database -- a tool for the analysis of transcription regulatory associations in Saccharomyces cerevisiae
2008 Update: YEASTRACT-DISCOVERER -- new tools to improve the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae
2011 Update: YEASTRACT: providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface.
2008 Update: YEASTRACT-DISCOVERER -- new tools to improve the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae
2011 Update: YEASTRACT: providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface.
This record last updated: 03-03-2008