Reconstruct complete protein structures from their alpha-carbon description.
Highlights:
SABBAC is an on-line service devoted to protein backbone reconstruction from alpha-carbon trace.
It is based on the assembly of fragments taken from a library of reduced size, selected from the encoding of the protein trace in a hidden Markov model-derived structural alphabet.
The assembly of the fragments is achieved by a greedy algorithm, using an energy-based scoring. Alpha-carbon coordinates remain unaffected.
SABBAC simply positions the missing backbone atoms, no further refinement is performed.
