SPRING -- a tool for the analysis of genome rearrangement using reversals and block-interchanges

URL:
http://algorithm.cs.nthu.edu.tw/tools/SPRING/
What you can do:
Analyze genome rearrangement between two chromosomal genomes.
Highlights:
  • SPRING is a tool for the analysis of genome rearrangement between two chromosomal genomes using reversals and/or block-interchanges.
  • It takes two or more chromosomes as its input and then computes a minimum series of reversals and/or block-interchanges between any two input chromosomes for transforming one chromosome into another.
  • The input of SPRING can be either bacterial-size sequences or gene/landmark orders.
  • If the input is a set of chromosomal sequences then the SPRING will automatically search for identical landmarks, which are homologous/conserved regions shared by all input sequences.
  • SPRING also computes the breakpoint distance between any pair of two chromosomes.
  • In addition, SPRING shows phylogenetic trees that are reconstructed based on the rearrangement and breakpoint distance matrixes.
Keywords:
  • genome rearrangement analysis tool
  • chromosome breakpoint distance calculation tool
Literature & Tutorials:
PubMed Link: SPRING -- a tool for the analysis of genome rearrangement using reversals and block-interchanges
This record last updated: 08-05-2006
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