CanGEM -- Cancer GEnome Mine

URL:

http://www.cangem.org/

What you can do:

A public database for storing clinical information about tumor samples and microarray data, emphasizing array comparative genomic hybridization (aCGH) and data mining of gene copy number changes.

Highlights:

CanGEM supports the MIAME standard and in addition, stores clinical information using standardized controlled vocabularies whenever possible.
Microarray probes are re-annotated with their physical coordinates in the human genome and aCGH data is analyzed to yield gene-specific copy numbers.
Users can build custom datasets by querying for specific clinical sample characteristics or copy number changes of individual genes.
Aberration frequencies can be calculated for these datasets, and the data can be visualized on the human genome map with gene annotations.
The original data files are available for more detailed analysis.

Keywords:

Chromosome Mapping
Gene Dosage
Gene Expression Profiling
Human Genome
Neoplasms
Cancer
aCGH
array comparative genomic hybridization
gene copy number

Literature & Tutorials:

PubMed Link: CanGEM: mining gene copy number changes in cancer

This record last updated: 04-16-2008

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