CORUM -- the Comprehensive Resource of Mammalian protein complexes
What you can do:
Search a collection of experimentally verified mammalian protein complexes.
Highlights:
- CORUM is a database that provides a manually curated repository of experimentally characterized protein complexes from mammalian organisms, mainly human (64%), mouse (16%) and rat (12%).
- The new CORUM 2.0 release encompasses 2837 protein complexes offering the largest and most comprehensive publicly available dataset of mammalian protein complexes.
- The dataset is built from 3198 different genes, representing approximately 16% of the protein coding genes in humans.
- Each protein complex is described by a protein complex name, subunit composition, function as well as the literature reference that characterizes the respective protein complex.
- Recent developments include mapping of functional annotation to Gene Ontology terms as well as cross-references to Entrez Gene identifiers.
- A 'Phylogenetic Conservation' analysis tool was implemented that analyses the potential occurrence of orthologous protein complex subunits in mammals and other selected groups of organisms.
- This allows one to predict the occurrence of protein complexes in different phylogenetic groups.
Keywords:
- Humans
- Mice
- Multiprotein Complexes
- Rats
- protein complexes
Literature & Tutorials:
This record last updated: 02-24-2010