SuperCAT -- multilocus sequence typing database of Bacillus cereus bacteria

What you can do:
A supertree database for combined and integrative multilocus sequence typing analysis of the Bacillus cereus group of bacteria.
Highlights:
  • The Bacillus cereus group of bacteria is an important group including mammalian and insect pathogens, such as B. anthracis, the anthrax bacterium, B. thuringiensis, used as a biological pesticide and B. cereus, often involved in food poisoning incidents.
  • To characterize the population structure and epidemiology of these bacteria, five separate multilocus sequence typing (MLST) schemes have been developed, which makes results difficult to compare.
  • We have developed a database that compiles and integrates MLST data from all five schemes for the B. cereus group.
  • Supertree techniques were used to combine the phylogenetic information from analysis of all schemes and datasets, in order to produce an integrated view of the B. cereus group population.
  • The database currently contains strain information and sequence data for 1029 isolates and 26 housekeeping gene fragments, which can be searched by keywords, MLST scheme, or sequence similarity.
  • Supertrees can be browsed according to various criteria such as species, isolate source, or genetic distance, and subtrees containing strains of interest can be extracted.
  • Besides analysis of the available data, the user has the possibility to enter her/his own sequences and compare them to the database and/or include them into the supertree reconstructions.
Keywords:
  • Bacillus anthracis
  • Bacillus cereus
  • Bacillus thuringiensis
  • Bacterial Typing Techniques
  • supertree
  • bacteria
  • Bacillus
  • multilocus sequence typing
  • pathogen
This record last updated: 04-29-2008
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