SuperCAT -- multilocus sequence typing database of Bacillus cereus bacteria
What you can do:
A supertree database for combined and integrative multilocus sequence typing analysis of the Bacillus cereus group of bacteria.
Highlights:
- The Bacillus cereus group of bacteria is an important group including mammalian and insect pathogens, such as B. anthracis, the anthrax bacterium, B. thuringiensis, used as a biological pesticide and B. cereus, often involved in food poisoning incidents.
- To characterize the population structure and epidemiology of these bacteria, five separate multilocus sequence typing (MLST) schemes have been developed, which makes results difficult to compare.
- We have developed a database that compiles and integrates MLST data from all five schemes for the B. cereus group.
- Supertree techniques were used to combine the phylogenetic information from analysis of all schemes and datasets, in order to produce an integrated view of the B. cereus group population.
- The database currently contains strain information and sequence data for 1029 isolates and 26 housekeeping gene fragments, which can be searched by keywords, MLST scheme, or sequence similarity.
- Supertrees can be browsed according to various criteria such as species, isolate source, or genetic distance, and subtrees containing strains of interest can be extracted.
- Besides analysis of the available data, the user has the possibility to enter her/his own sequences and compare them to the database and/or include them into the supertree reconstructions.
Keywords:
- Bacillus anthracis
- Bacillus cereus
- Bacillus thuringiensis
- Bacterial Typing Techniques
- supertree
- bacteria
- Bacillus
- multilocus sequence typing
- pathogen
This record last updated: 04-29-2008