CPC -- Coding Potential Calculator
What you can do:
Assess the protein-coding potential of transcripts using sequence features and support vector machine.
Highlights:
- We developed a support vector machine-based classifier, named Coding Potential Calculator (CPC), to assess the protein-coding potential of a transcript based on six biologically meaningful sequence features.
- Tenfold cross-validation on the training dataset and further testing on several large datasets showed that CPC can discriminate coding from noncoding transcripts with high accuracy.
- Furthermore, CPC also runs an order-of-magnitude faster than a previous state-of-the-art tool and has higher accuracy.
- In addition to predicting the coding potential of the input transcripts, the CPC web server also graphically displays detailed sequence features and additional annotations of the transcript that may facilitate users' further investigation.
Keywords:
- Expressed Sequence Tags
- Genetic Code
- Genetic Vectors
- Molecular Sequence Data
- Protein Biosynthesis
- Proteins
- RNA
- Transcription
- protein coding
- protein-coding
- support vector machine
Literature & Tutorials:
This record last updated: 06-04-2008