TargetRNA -- a tool for predicting targets of small RNA action in bacteria

What you can do:
Identify targets of small (non-coding) RNA action.
Highlights:
  • TargetRNA takes as input a genomic sequence that may correspond to an sRNA gene.
  • TargetRNA then uses a dynamic programming algorithm to search each annotated message in a specified genome for mRNAs that evince basepair-binding potential to the input sRNA sequence.
  • Based on the calculated basepair-binding potential of each message with the given sRNA regulator, TargetRNA outputs a ranked list of candidate mRNA targets along with the predicted basepairing interaction of each target to the sRNA.
  • The predictive performance of TargetRNA has been validated experimentally in several bacterial organisms.
Keywords:
  • sRNA
  • small RNA
  • bacteria RNA
This record last updated: 07-21-2008
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