GenoSNP -- SNP genotyping
What you can do:
A Variational Bayes within-sample SNP genotyping algorithm that does not require a reference population.
Highlights:
- We have developed a SNP genotyping algorithm for the Illumina Infinium SNP genotyping assay that is entirely within-sample and does not require the need for a population of control samples nor parameters derived from such a population.
- Our algorithm exhibits high concordance with current methods and > 99% call accuracy on HapMap samples.
- The ability to call genotypes using only within-sample information makes the method computationally light and practical for studies involving small sample sizes and provides a valuable independent quality control metric for other population based approaches.
Keywords:
- SNP
- single nucleotide polymorphism
- SNP genotyping
- genotyping algorithm
- genotyping assay
Literature & Tutorials:
This record last updated: 08-04-2008