dPattern -- Binding Site Discovery in Human Genome using a Discriminate Pattern Approach
What you can do:
Transcription factor binding site discovery in human genome using a discriminative pattern analysis.
Highlights:
- Transcription factor binding sites (TFBSs) are typically short in length, thus search with a profile model from known TFBSs produces many false positives.
- When combined with additional information, sensitivity and specificity of TFBS search can be improved significantly.
- By modifying our previous REFINEMENT approach, we developed dPattern that searches for occurrences of TFBSs in the promotor regions of up/down regulated or random genes.
Keywords:
- Binding Sites
- Gene Expression Profiling
- Pattern Recognition
- Protein Binding
- Transcription Factors
- binding site discovery
- transcription factor binding site
- TFBS
- pattern analysis
Literature & Tutorials:
This record last updated: 08-07-2008