GENOMEPOP -- a program to simulate genomes in populations
What you can do:
Software that allows the forward simulation of DNA sequences in a metapopulation context under a variety of conditions.
Highlights:
- GenomePop has many interesting characteristics for simulating SNPs or DNA sequences under complex evolutionary and demographic models. These features make it unique with respect to other simulation tools.
- Namely, the possibility of forward simulation under General Time Reversible (GTR) mutation or GTRxMG94 codon models with intra-codon recombination, arbitrary, user-defined, migration patterns, diploid or haploid models, constant or variable population sizes, etc.
- It also allows simulation of fitness-based selection under different distributions of mutational effects.
- Under the 2-allele model it allows the simulation of recombination hot-spots, the definition of different frequencies in different populations, etc.
- GenomePop can also manage large DNA fragments.
- In addition, it has a scaling option to save computation time when simulating large sequences and population sizes under complex demographic and evolutionary situations.
Keywords:
- Evolution
- Gene Frequency
- population genetics
Literature & Tutorials:
This record last updated: 08-11-2008