SnoReport -- computational identification of snoRNAs with unknown targets
What you can do:
Identify small nucleolar RNAs with unknown targets.
Highlights:
- The discovery of 'orphan' snoRNAs, which either have no known target, or which target ordinary protein-coding mRNAs, however, begs the question whether this class of 'housekeeping' non-coding RNAs is much more widespread and might have a diverse set of regulatory functions.
- In order to approach this question, we present here a combination of RNA secondary structure prediction and machine learning that is designed to recognize the two major classes of snoRNAs, box C/D and box H/ACA snoRNAs, among ncRNA candidate sequences.
Keywords:
- snoRNA
- small nucleolar RNA
Literature & Tutorials:
This record last updated: 12-9-2008