ParCrys -- protein crystallization propensity prediction
What you can do:
A Parzen Window approach to estimate a protein's propensity to produce diffraction-quality crystals.
Highlights:
- The Protein Data Bank (PDB) provided training data whilst the databases TargetDB and PepcDB were used to define feature selection data as well as test data independent of feature selection and training.
- ParCrys outperforms the OB-Score, SECRET and CRYSTALP on the data examined, with accuracy and Matthews correlation coefficient values of 79.1% and 0.582, respectively (74.0% and 0.227, respectively, on data with a 'real-world' ratio of positive:negative examples).
Keywords:
- Crystallization
- Protein Conformation
- Protein Sequence Analysis
- Protein Ultrastructure
Literature & Tutorials:
This record last updated: 01-07-2009