PIPs -- protein-protein interaction prediction database
What you can do:
A resource for studying human protein-protein interactions.
Highlights:
- PIPs contains predictions of >37,000 high probability interactions of which >34,000 are not reported in the interaction databases HPRD, BIND, DIP or OPHID.
- The interactions in PIPs were calculated by a Bayesian method that combines information from expression, orthology, domain co-occurrence, post-translational modifications and sub-cellular location.
- The predictions also take account of the topology of the predicted interaction network.
- The web interface to PIPs ranks predictions according to their likelihood of interaction broken down by the contribution from each information source and with easy access to the evidence that supports each prediction.
- Where data exists in OPHID, HPRD, DIP or BIND for a protein pair this is also reported in the output tables returned by a search.
- A network browser is included to allow convenient browsing of the interaction network for any protein in the database.
Keywords:
- gene co-expression
- orthology
- co-localization
- domain co-occurrence
- post-translational modification
- protein interaction predictor
- interactome
- protein-protein interactions
Literature & Tutorials:
This record last updated: 01-28-2009