miROrtho -- miRNA Orthology Database
What you can do:
Search for animal microRNA genes.
Highlights:
- The miROrtho database presents the results of a comprehensive computational survey of miRNA gene candidates across the majority of sequenced metazoan genomes.
- It has a three-tier analysis pipeline: (i) an SVM-based ab initio screen for potent hairpins, plus homologs of known miRNAs, (ii) an orthology delineation procedure and (iii) an SVM-based classifier of the ortholog multiple sequence alignments.
- The web interface provides direct access to putative miRNA annotations, ortholog multiple alignments, RNA secondary structure conservation, and sequence data.
- The miROrtho data are conceptually complementary to the miRBase catalog of experimentally verified miRNA sequences, providing a consistent comparative genomics perspective as well as identifying many novel miRNA genes with strong evolutionary support.
Keywords:
- miRNA
- microRNA
- microRNA prediction
Literature & Tutorials:
PubMed Link: miROrtho: computational survey of microRNA genes
This record last updated: 03-25-2009