GeNMR -- GEnerate NMR structure web server
URL:
What you can do:
Generate 3D protein structures using NOE-derived distance restraints and NMR chemical shifts
Highlights:
- GeNMR is a web server for rapidly generating accurate 3D protein structures using sequence data, NOE-based distance restraints and/or NMR chemical shifts as input.
- It accepts distance restraints in XPLOR or CYANA format as well as chemical shift files in either SHIFTY or BMRB formats.
- The web server produces an ensemble of PDB coordinates for the protein within 15-25 min.
- It combines genetic algorithms for structure optimization along with homology modeling, chemical shift threading, torsion angle and distance predictions from chemical shifts/NOEs as well as ROSETTA-based structure generation and simulated annealing with XPLOR-NIH to generate and/or refine protein coordinates.
- GeNMR was developed to facilitate rapid, user-friendly structure determination of protein structures via NMR spectroscopy.
Keywords:
- NMR
- nuclear magnetic resonance spectrometry
- chemical shift
- NOE-derived distance restraint
- protein structure
Literature & Tutorials:
This record last updated: 08-11-2009