COPS -- Classification of Protein Structures

What you can do:
Retrieve information about protein structural similarity.
Highlights:
  • The COPS web server provides access to the complete repertoire of known protein structures and protein structural domains. The classification system encodes pairwise structural similarities as quantified metric relationships.
  • The resulting metrical structure is mapped to a hierarchical tree, which is largely equivalent to the structure of a file browser.
  • The Fold Space Navigator is a tool that makes navigation in fold space as convenient as browsing through a file system.
  • Pairwise structural similarities among the domains can be visualized and inspected instantaneously.
  • COPS is updated weekly and stays concurrent with the PDB repository.
  • The server also exposes the COPS classification pipeline. Newly determined structures uploaded to the server are chopped into domains, the locations of the new domains in the classification tree are determined, and their neighborhood can be immediately explored through the Fold Space Navigator.
Keywords:
  • protein structure alignment
  • PDB
  • protein structural domain
Literature & Tutorials:
This record last updated: 08-13-2009
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