NetCSSP -- Neural networks for calculating Contact-dependent Secondary Structure Propensity

URL:
http://cssp2.sookmyung.ac.kr/
What you can do:
Use to detect non-native secondary structure propensities in protein sequences.
Highlights:
  • NetCSSP implements the latest version of the CSSP algorithm and provides a Flash chart-based graphic interface that enables an interactive calculation of CSSP values for any user-selected regions in a given protein sequence.
  • This feature also can quantitatively estimate the mutational effect on changes in native or non-native secondary structural propensities in local sequences.
  • This web tool provides precalculated non-native secondary structure propensities for over 1,400,000 fragments that are seven-residues long, collected from PDB structures.
  • They are searchable for chameleon subsequences that can serve as the core of amyloid fibril formation.
Keywords:
  • amyloid fibril formation
  • non-native secondary structure prediction
  • protein secondary structure
Literature & Tutorials:
PubMed Link: NetCSSP: web application for predicting chameleon sequences and amyloid fibril formation
This record last updated: 08-18-2009
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