PHEMTO -- Protein pH-dependent Electric Moment TOols
What you can do:
Use to evaluate protein electrostatic characteristics in relations to molecular recognition.
Highlights:
- PHEMTO is a web server with features for analysis of protein molecular interactions: Electric/dipole moments, their pH-dependence and in silico charge mutagenesis effects on these properties as well as alternative algorithms for electric/dipole moment computation--Singular value decomposition of electrostatic potential (EP) to account for reaction field.
- The implementation is based on long-term experience--PHEI mean field electrostatics and PHEPS server for evaluation of global and local pH-dependent properties.
- It also offers features for analysis of protein molecular interactions.
- The input is comprised of the atomic coordinate file in Protein Data Bank format. The advanced user is provided with a special input section for addition of non-polypeptide charges.
- The output covers actually full electrostatic characteristics but special emphasis is given to electric/dipole moments and their interactive visualization.
Keywords:
- protein-protein interaction
- protein electrostatic interaction
- protein molecular recognition
- dipole moments
- protein interaction network
Literature & Tutorials:
PubMed Link: PHEMTO: protein pH-dependent electric moment tools
This record last updated: 08-20-2009