SARA -- Server for function Analysis of RnA structures
What you can do:
Search for pair-wise alignment of RNA structures.
Highlights:
- SARA is a web server for structure-based RNA function assignment.
- It relies on the SARA program, which aligns two RNA structures based on a unit-vector root-mean-square approach.
- The likely accuracy of the SARA alignments is assessed by three different P-values estimating the statistical significance of the sequence, secondary structure and tertiary structure identity scores, respectively.
- The benchmarks, which relied on a set of 419 RNA structures with known SCOR structural class, indicate that at a negative logarithm of mean P-value higher or equal than 2.5, SARA can assign the correct or a similar SCOR class to 81.4% and 95.3% of the benchmark set, respectively.
Keywords:
- RNA structure
- RNA function annotation
- non-coding RNA
Literature & Tutorials:
This record last updated: 08-25-2009