Virus Genotyping Tools
What you can do:
Find information about virus genomes.
Highlights:
- Virus Genotyping tools are together a rapid high-throughput-genotyping system.
- They cover the following viruses: HIV-1; HIV-2; HTLV-1; Hepatitis B; Hepatitis C; human herpesvirus 8; and human papillomavirus.
- The method involves the alignment of a query sequence with a carefully selected set of pre-defined reference strains, followed by phylogenetic analysis of multiple overlapping segments of the alignment using a sliding window.
- Each segment of the query sequence is assigned the genotype and sub-genotype of the reference strain with the highest bootstrap (>70%) and bootscanning (>90%) scores.
- Results from all windows are combined and displayed graphically using color-coded genotypes.
- The new Virus-Genotyping Tools provide accurate classification of recombinant and non-recombinant viruses and are currently being assessed for their diagnostic utility.
Keywords:
- virus diagnosis
- recombinant virus
- non-recombinant
- virus classification
- virus genotyping
- Human Immunodeficiency Virus
- HPV
- HIV
- human papillomavirus
Literature & Tutorials:
This record last updated: 09-25-2009