ProLoc-GO -- Protein Localization Prediction based on Gene Ontology

What you can do:
Use for sequence-based prediction of protein subcellular localization.
Highlights:
  • ProLoc-GO is a web-based method that mines informative GO terms to predict protein subcellular localization.
  • For each protein, BLAST is used to obtain a homology with a known accession number to the protein for retrieving the GO annotation.
  • A large number n of all annotated GO terms that have ever appeared are then obtained from a large set of training proteins.
  • A novel genetic algorithm based method (named GOmining) combined with a classifier of support vector machine (SVM) is proposed to simultaneously identify a small number m out of the n GO terms as input features to SVM, where m <
Keywords:
  • protein subcellular localization
  • protein localization
  • protein cellular localization
  • protein localization prediction
  • gene ontology
This record last updated: 01-05-2010
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