MiSTdb -- Microbial Signal Transduction Database

URL:
http://mistdb.com/
What you can do:
Find information about communication networks in microbes.
Highlights:
  • The MiST2 database identifies and catalogs the repertoire of signal transduction proteins in microbial genomes.
  • These are identified by searching protein sequences for specific domain profiles that implicate a protein in signal transduction.
  • It contains features including the following: draft genomes; extracytoplasmic function (ECF) sigma factor protein identification; enhanced classification of signaling proteins; novel, high-quality domain models for identifying histidine kinases and response regulators; neighboring two-component genes; gene cart; better search capabilities; enhanced taxonomy browser; advanced genome browser; and a modern, biologist-friendly web interface.
  • MiST2 currently contains 966 complete and 157 draft bacterial and archaeal genomes, which collectively contain more than 245 000 signal transduction proteins.
  • The majority (66%) of these are one-component systems, followed by two-component proteins (26%), chemotaxis (6%), and finally ECF factors (2%).
Keywords:
  • signal transduction
  • E. coli
  • Staphylococcus aureus
  • host-recognition
  • antibiotic resistance
  • human pathogens
Literature & Tutorials:
PubMed Link: The MiST2 database: a comprehensive genomics resource on microbial signal transduction
This record last updated: 02-16-2010
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