dbDEPC -- DataBase of Differentially Expressed Proteins in human Cancers
What you can do:
Find information about proteins implicated in cancer.
Highlights:
- dbDEPC is a database with the goal of collecting curated cancer proteomics data, providing a resource for information on protein-level expression changes, and exploring protein profile differences among different cancers.
- dbDEPC currently contains 1803 proteins differentially expressed in 15 cancers, curated from 65 mass spectrometry (MS) experiments in peer-reviewed publications.
- It also includes low-throughput experiment data from the same literatures and cancer-associated genes from external databases.
- It associates differential proteins with important structural variations in the human genome, such as copy number variations or single nucleotide polymorphisms, which might be helpful for explaining changes in protein expression at the DNA level.
- Data in dbDEPC can be queried by protein identifier, description or sequence; the retrieved protein entry provides the differential expression pattern seen in cancers, along with detailed annotations.
- dbDEPC is expected to be a reference database for cancer signatures at the protein level.
Keywords:
- cancer
- human cancer
- mass spectrometry
- cancer protein pathway
- cancer protein
- protein differential expression
- cancer biomarker
- biomarker
Literature & Tutorials:
This record last updated: 03-15-2010