GIS -- Gangsta+ Internet Services

What you can do:
Perform protein structure alignment.
Highlights:
  • GIS is a web service for analysis of protein structures that are sequentially or non-sequentially similar was generated.
  • GANGSTA+ can detect non-sequential structural analogs for proteins stated to possess novel folds.
  • Since GANGSTA+ ignores the polypeptide chain connectivity of secondary structure elements (i.e. alpha-helices and beta-strands), it is able to detect structural similarities also between proteins whose sequences were reshuffled during evolution.
  • GIS provides the resulting protein structure alignments as a public web-based service.
  • Users can upload their own protein structures for pairwise protein structure comparison, alignment against all protein structures of the ASTRAL40 database (SCOP version 1.75) or symmetry analysis.
Keywords:
  • protein structure alignment
  • intrinsic rotational symmetry
  • ASTRAL40
  • Connectivity independent protein-structure alignment
This record last updated: 07-16-2010
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